{"id":41515,"date":"2019-07-31T16:10:25","date_gmt":"2019-07-31T08:10:25","guid":{"rendered":"https:\/\/www.gene-optimal.com\/?p=41515"},"modified":"2019-09-09T15:04:29","modified_gmt":"2019-09-09T07:04:29","slug":"ntm-meta","status":"publish","type":"post","link":"https:\/\/www.gene-optimal.com\/ntm-meta\/","title":{"rendered":"\u975e\u7ed3\u6838\u5206\u679d\u6746\u83cc\u7684\u9274\u5b9a\u53ca\u836f\u654f\u6027\u5206\u6790"},"content":{"rendered":"

\u6211\u56fd\u5386\u6b21\u7ed3\u6838\u75c5\u6d41\u884c\u75c5\u5b66\u8c03\u67e5\u8d44\u6599\u663e\u793a\uff0c\u975e\u7ed3\u6838\u5206\u679d\u6746\u83cc\uff08NTM\uff09\u5206\u79bb\u7387\u4ece1990\u5e74\u76844.9%\u5347\u81f32000\u5e74\u768411.1%\uff0c2010\u5e74\u4e3a22.9%\uff0cNTM\u7684\u5206\u79bb\u7387\u6301\u7eed\u589e\u9ad8\uff0c\u8fd9\u57fa\u672c\u53cd\u6620\u51fa\u6211\u56fdNTM\u75c5\u5448\u660e\u663e\u4e0a\u5347\u7684\u6001\u52bf\uff0c\u5e76\u5df2\u6210\u4e3a\u5a01\u80c1\u4eba\u7c7b\u5065\u5eb7\u7684\u91cd\u8981\u516c\u5171\u536b\u751f\u95ee\u9898\u3002NTM\u9274\u522b\u8bca\u65ad\u8f83\u4e3a\u56f0\u96be\uff0c\u4e34\u5e8a\u4e0aNTM\u80ba\u75c5\u4e0e\u80ba\u7ed3\u6838\u5728\u75c7\u72b6\u3001\u4f53\u5f81\u53ca\u5f71\u50cf\u5b66\u8868\u73b0\u65b9\u9762\u5747\u5177\u6709\u5f88\u5927\u7684\u76f8\u4f3c\u6027\uff0c\u4f46\u65e0\u8bba\u4ece\u75c5\u539f\u5b66\u8fd8\u662f\u6cbb\u7597\u4e0a\uff0c\u90fd\u4e0e\u80ba\u7ed3\u6838\u6709\u4e00\u5b9a\u7684\u533a\u522b\u3002NTM\u80ba\u75c5\u65e0\u6cd5\u901a\u8fc7\u75f0\u5206\u679d\u6746\u83cc\u6297\u9178\u67d3\u8272\u8fdb\u884c\u9274\u522b\uff0c\u8981\u660e\u786e\u75c5\u539f\u5b66\u8bca\u65ad\u987b\u8fdb\u884c\u83cc\u79cd\u9274\u5b9a\uff0c\u800c\u91c7\u7528\u7ecf\u5178\u7684\u75f0\u57f9\u517b\u53ca\u83cc\u79cd\u9274\u5b9a\u65b9\u6cd5\u9700\u89818\u5468\u5de6\u53f3\u7684\u65f6\u95f4\u3002\u5728\u4e34\u5e8a\u5de5\u4f5c\u4e2d\uff0c\u5f88\u591a\u80ba\u90e8\u75be\u75c5\u60a3\u8005\u6700\u521d\u8bca\u65ad\u4e3a\u201c\u80ba\u7ed3\u6838\u201d\uff0c\u4f46\u6570\u5468\u8fc7\u540e\uff0c\u83cc\u79cd\u9274\u5b9a\u62a5\u544a\u5374\u63d0\u793a\u4e3aNTM\u751f\u957f\uff0c\u4e14\u5bf9\u51e0\u4e4e\u6240\u6709\u7684\u4e00\u7ebf\u6297\u7ed3\u6838\u836f\u7269\u5747\u8010\u836f\uff0c\u56e0\u800c\u4e0d\u5f97\u4e0d\u8c03\u6574\u6216\u66f4\u6362\u6240\u6709\u7684\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n

 <\/p>\n

\u4e00\u3001\u4ec0\u4e48\u662f\u975e\u7ed3\u6838\u5206\u679d\u6746\u83cc\uff1f<\/span><\/p>\n

 <\/p>\n

\u975e\u7ed3\u6838\u5206\u679d\u6746\u83cc\uff08NTM\uff09\u6307\u9664MTB\u590d\u5408\u7fa4\u548c\u9ebb\u98ce\u5206\u679d\u6746\u83cc\u4ee5\u5916\u7684\u4e00\u5927\u7c7b\u5206\u679d\u6746\u83cc\u603b\u79f0\uff0c\u662f\u4e00\u79cd\u73af\u5883\u751f\u957f\u83cc\uff0c\u5728\u81ea\u7136\u754c\u5e7f\u6cdb\u5b58\u5728\uff0c\u76ee\u524d\u5168\u4e16\u754c\u5df2\u53d1\u73b0NTM\u7ea6154\u79cd\uff0c\u4f46\u53ea\u8981\u5c11\u6570\u662f\u81f4\u75c5\u83cc\uff0c\u5c5e\u4e8e\u6761\u4ef6\u81f4\u75c5\u83cc\uff0c\u4e3b\u8981\u4fb5\u72af\u80ba\u90e8\uff0c\u8fd1\u5e74\u6765\u56fd\u5185NTM\u75c5\u53d1\u75c5\u7387\u4e0d\u65ad\u589e\u52a0\uff0c\u4ee5\u9e1f\u590d\u5408\u5206\u679d\u6746\u83cc\u3001\u582a\u8428\u65af\u5206\u679d\u6746\u83cc\u548c\u87fe\u870d\u5206\u679d\u6746\u83cc\u6700\u4e3a\u5e38\u89c1\u3002\u4ece\u5bf9\u4e34\u5e8a\u6307\u5bfc\u610f\u4e49\u8003\u8651\uff0c\u5c06NTM\u7b80\u5355\u5206\u4e3a\u5feb\u751f\u957f\u5206\u679d\u6746\u83cc\uff08RGM\uff09\u548c\u6162\u751f\u957f\u5206\u679d\u6746\u83cc\uff08SGM\uff09\uff0c\u5373\u53ef\u5bf9\u7528\u836f\u9009\u62e9\u63d0\u4f9b\u6709\u76ca\u4fe1\u606f\u3002\u4e34\u5e8a\u6700\u5e38\u89c1\u7684\u6709\u4e34\u5e8a\u4ef7\u503c\u7684RGM\u5305\u62ec\u8113\u80bf\u5206\u679d\u6746\u83cc\u3001\u5076\u7136\u5206\u679d\u6746\u83cc\u548c\u9f9f\u5206\u679d\u6746\u83cc\uff0cRGM\u611f\u67d3\u901a\u5e38\u9009\u7528\u5927\u73af\u5185\u916f\u7c7b\u3001\u6c28\u57fa\u7cd6\u82f7\u7c7b\u548c\u6c1f\u55b9\u8bfa\u916e\u7c7b\u7b49\u836f\u7269\u6cbb\u7597\u3002\u6700\u5e38\u89c1\u7684\u6709\u4e34\u5e8a\u4ef7\u503c\u7684SGM\u5305\u62ec\u9e1f\u5206\u679d\u6746\u83cc\u590d\u5408\u7fa4\uff08MAC\uff0c\u4e3b\u8981\u5305\u62ec\u9e1f\u5206\u679d\u6746\u83cc\u548c\u80de\u5185\u5206\u679d\u6746\u83cc\uff09\u3001\u582a\u8428\u65af\u5206\u679d\u6746\u83cc\u53ca\u87fe\u870d\u5206\u679d\u6746\u83cc\u7b49\uff0c\u6cbb\u7597\u901a\u5e38\u9009\u53d6\u5927\u73af\u5185\u916f\u7c7b\u548c\u5229\u798f\u9709\u7d20\u7c7b\u836f\u7269\uff0c\u6709\u65f6\u5019\u52a0\u7528\u6ce8\u5c04\u7c7b\u6297\u7ed3\u6838\u836f\u7269\u3002<\/p>\n

 <\/p>\n

\u4e8c\u3001\u5e38\u7528\u7684NTM\u9274\u5b9a\u65b9\u6cd5<\/span><\/p>\n

 <\/p>\n

\u7531\u4e8e\u5404\u5927\u533b\u9662\u5bf9\u4e8e\u975e\u7ed3\u6838\u5206\u679d\u6746\u83cc\u7684\u8bca\u65ad\u6c34\u5e73\u548c\u6807\u51c6\u53c2\u5dee\u4e0d\u9f50\uff0c\u8bef\u8bca\u7387\u8f83\u9ad8\uff0c\u4e3a\u4fc3\u8fdb\u5b9e\u9a8c\u5ba4NTM\u68c0\u9a8c\u6c34\u5e73\u7684\u63d0\u9ad8\uff0c\u540c\u65f6\u63d0\u9ad8\u4e34\u5e8a\u533b\u751f\u5bf9\u5b9e\u9a8c\u5ba4\u7ed3\u679c\u7684\u6b63\u786e\u8ba4\u77e5\uff0c\u4e2d\u534e\u533b\u5b66\u4f1a\u7ed3\u6838\u75c5\u5b66\u5206\u4f1a\u7ec4\u7ec7\u6d41\u884c\u75c5\u3001\u4e34\u5e8a\u548c\u5b9e\u9a8c\u5ba4\u9886\u57df\u4e13\u5bb6\u5c31NTM\u76f8\u5173\u5b9e\u9a8c\u5ba4\u8bca\u65ad\u9886\u57df\u7684\u91cd\u8981\u95ee\u9898\u8fdb\u884c\u8ba8\u8bba\uff0c2016\u5e74\u64b0\u5199\u4e86\u6700\u65b0\u7684\u300a\u975e\u7ed3\u6838\u5206\u679d\u6746\u83cc\u75c5\u5b9e\u9a8c\u5ba4\u8bca\u65ad\u4e13\u5bb6\u5171\u8bc6\u300b\u3002<\/p>\n

\u4e2d\u534e\u533b\u5b66\u4f1a\u7ed3\u6838\u75c5\u5b66\u5206\u4f1a\u300a\u975e\u7ed3\u6838\u5206\u679d\u6746\u83cc\u75c5\u5b9e\u9a8c\u5ba4\u8bca\u65ad\u4e13\u5bb6\u5171\u8bc6\u300b<\/span><\/p>\n

\u6587\u4e2d\u6307\u51fa\uff0c\u4f20\u7edf\u7684\u6839\u636e\u751f\u5316\u548c\u9274\u522b\u57f9\u517b\u57fa\u8fdb\u884c\u83cc\u79cd\u9274\u5b9a\u7684\u65b9\u6cd5\u4e0d\u4f46\u8017\u65f6\uff0c\u800c\u4e14\u4e0d\u80fd\u5b8c\u5168\u5c06\u8bb8\u591aNTM\u83cc\u79cd\u9274\u5b9a\u51fa\u6765\uff0c\u56e0\u6b64\u5df2\u4e0d\u5e38\u7528\u3002\u73b0\u9636\u6bb5\u5e38\u7528\u7684\u4e34\u5e8a\u83cc\u79cd\u9274\u5b9a\u65b9\u6cd5\u6709\u4ee5\u4e0b\u51e0\u79cd\uff1a<\/p>\n

1. \u5bf9\u785d\u57fa\u82ef\u7532\u9178\uff08PNB\uff09\u9009\u62e9\u6027\u57f9\u517b\u57fa\u6cd5<\/strong><\/p>\n

\u6b64\u65b9\u6cd5\u5728\u6211\u56fd\u5e7f\u6cdb\u5f00\u5c55\uff0cNTM\u53ef\u5728\u542b500 mg\/L PNB\u7684\u7f57\u6c0f\u57f9\u517b\u57fa\u4e0a\u751f\u957f\uff0c\u800cMTC\u4e0d\u8010\u53d7\uff0c\u8f83\u591a\u7ed3\u679c\u8868\u660e\u6b64\u65b9\u6cd5\u53ef\u7528\u4e8e\u9274\u5b9aMTC\u548cNTM\u3002<\/p>\n

2. MPT64\u6297\u539f\u68c0\u6d4b\u6cd5<\/strong><\/p>\n

MPT64\u6297\u539f\u662fMTC\u5728\u6db2\u4f53\u57f9\u517b\u57fa\u4e2d\u751f\u957f\u65f6\u4e3b\u8981\u5206\u6ccc\u7684\u86cb\u767d\u4e4b\u4e00\uff0cNTM\u57f9\u517b\u6ee4\u6db2\u4e2d\u591a\u4e0d\u5b58\u5728\u6b64\u5206\u6ccc\u86cb\u767d\uff0c\u7531\u6b64\u53ef\u4ee5\u8fdb\u884c\u521d\u6b65\u83cc\u79cd\u9274\u5b9a\u3002\u68c0\u6d4b\u65b9\u6cd5\u5927\u591a\u91c7\u7528\u514d\u75ab\u5c42\u6790\u6cd5\u68c0\u6d4b\u57f9\u517b\u6ee4\u6db2\u4e2dMPT4\u6297\u539f\u662f\u5426\u5b58\u5728\uff0c\u5177\u6709\u64cd\u4f5c\u7b80\u5355\u3001\u7528\u65f6\u77ed\u7b49\u4f18\u70b9\u3002\u6b64\u6280\u672f\u5177\u6709\u5f88\u9ad8\u7684\u654f\u611f\u5ea6\uff08\u591a\u6570\u62a5\u9053\u8d85\u8fc797%\uff09\u548c\u7279\u5f02\u5ea6\uff08\u591a\u6570\u62a5\u9053\u8d85\u8fc797%\uff09\u3002<\/p>\n

3. \u6838\u9178\u6269\u589e\u5b9e\u9a8c<\/strong><\/p>\n

PCR\u6280\u672f\uff0c\u7ed3\u6838\u75c5\u8bca\u65ad\u7684PCR\u8bd5\u5242\u76d2\u6269\u589e\u7684\u9776\u5e8f\u5217\u5f80\u5f80\u662fMTC\u4e2d\u7279\u5f02\u6027\u7684DNA\u5e8f\u5217\uff0c\u5982IS6110\u3001MPT64\u3001ESAT-6\u53caCFP-10\u7b49\u3002\u5c06PCR\u6280\u672f\u4e0e\u6d82\u7247\u548c\u57f9\u517b\u7ed3\u5408\u53ef\u7528\u4e8eNTM\u7684\u521d\u6b65\u7b5b\u67e5\u3002\u5bf9\u4e8e\u6d82\u7247\u9633\u6027\u6216\u662f\u57f9\u517b\u9633\u6027\u7684\u6807\u672c\uff0c\u5e73\u884c\u7684PCR\u6269\u589e\u83b7\u5f97\u9633\u6027\u7ed3\u679c\u63d0\u793a\u6837\u54c1\u4e2d\u5b58\u5728MTC\u83cc\uff0c\u53cd\u4e4b\uff0c\u5f53PCR\u4e3a\u9634\u6027\u7ed3\u679c\u65f6\uff0c\u5e94\u8003\u8651\u5b58\u5728NTM\u7684\u53ef\u80fd\uff0c\u4f46\u9700\u8981\u8fdb\u4e00\u6b65\u6838\u5b9e\u3002<\/p>\n

4. \u5206\u5b50\u8bca\u65ad\u6280\u672f<\/strong><\/p>\n

\u540c\u6e90\u57fa\u56e0\u6216\u5e8f\u5217\u6bd4\u8f83\uff0c\u901a\u8fc7\u5206\u6790\u540c\u6e90DNA\u5e8f\u5217\u7ec4\u6210\u5dee\u5f02\u9274\u5b9a\u7ec6\u83cc\u81f3\u79cd\u6c34\u5e73\uff0c\u53ef\u7528\u4e8e\u83cc\u79cd\u9274\u5b9a\u7684DNA\u5e8f\u5217\u65e2\u8981\u6c42\u5728\u4e0d\u540c\u7684\u83cc\u79cd\u95f4\u5177\u6709\u8f83\u9ad8\u7684\u5e8f\u5217\u4fdd\u5b88\u6027\uff0c\u5b9e\u73b0\u5e94\u7528\u901a\u7528\u5f15\u7269\u5bf9\u4e0d\u540c\u83cc\u79cd\u76ee\u6807\u5e8f\u5217\u7684\u6269\u589e\uff0c\u53c8\u8981\u6c42\u4e0d\u540c\u83cc\u79cd\u7684\u540c\u6e90\u5e8f\u5217\u5177\u6709\u4e00\u5b9a\u6c34\u5e73\u7684\u5dee\u5f02\uff0c\u4ee5\u5b9e\u73b0\u9274\u522b\u533a\u5206\u7684\u76ee\u7684\u3002\u76ee\u524d\u6700\u5e38\u7528\u7684\u540c\u6e90\u5e8f\u5217\u670916S RNA\u7f16\u7801\u57fa\u56e0\uff0816S DNA\uff09\u300116S-23S rRNA\u57fa\u56e0\u95f4\u533a\uff08ITS\uff09\u3001RNA\u805a\u5408\u9176\u7684\u03b2-\u4e9a\u57fa\uff08rpoB\uff09\u548c\u70ed\u4f11\u514b\u86cb\u767d65(hsp65)\u7684\u7f16\u7801\u57fa\u56e0\u3002<\/p>\n

5. \u4f9d\u636e\u7ec6\u83cc\u7ed3\u6784\u5dee\u5f02\u8fdb\u884c\u83cc\u79cd\u9274\u5b9a<\/strong><\/p>\n

\u9ad8\u6548\u6db2\u76f8\u5206\u6790\u7ec6\u80de\u58c1\u7684\u5206\u679d\u83cc\u9178\u78b3\u94fe\u7ed3\u6784\u548c\u86cb\u767d\u6210\u5206\u5728\u83cc\u4f53\u4e2d\u7684\u6bd4\u4f8b\u3002\u7ec6\u83cc\u7684\u8102\u8d28\u548c\u86cb\u767d\u8d28\u7684\u7ec4\u6210\u5177\u6709\u79cd\u5c5e\u7279\u5f02\u6027\uff0c\u8fd92\u79cd\u65b9\u6cd5\u5747\u5df2\u7ecf\u5efa\u7acb\u4e86\u5305\u542b\u4e30\u5bcc\u83cc\u79cd\u7684\u56fe\u8c31\u5e93\u7528\u4e8e\u7ed3\u679c\u6bd4\u5bf9\uff0c\u56e0\u6b64\u5177\u6709\u5f88\u9ad8\u7684\u9274\u522b\u80fd\u529b\u3002<\/p>\n

\u4ee5\u4e0a\u65b9\u6cd5\u5747\u7528\u4e8e\u4e34\u5e8a\u5206\u79bb\u682a\u7684\u9274\u5b9a\uff0c\u56e0\u6b64\u4e0d\u5229\u4e8e\u4e34\u5e8a\u7684\u53ca\u65f6\u8bca\u65ad\uff0c\u5728\u6211\u56fdNTM\u5206\u79bb\u7387\u4e0d\u65ad\u63d0\u9ad8\u60c5\u51b5\u4e0b\uff0c\u8feb\u4e8e\u5404\u79cd\u4e0d\u5229\u56e0\u7d20\uff0c\u6025\u5207\u9700\u8981\u4e00\u79cd\u65b9\u6cd5\u5229\u4e8e\u5feb\u901f\u3001\u7701\u65f6\u3001\u65b9\u4fbf\u3001\u53ef\u4fe1\u5ea6\u9ad8\u7684\u65b9\u6cd5\u7528\u4e8e\u83cc\u79cd\u9274\u5b9a\u3002<\/p>\n

\u4e8c\u4ee3\u6d4b\u5e8f\u6280\u672f\u8d8a\u6765\u8d8a\u591a\u5730\u5e94\u7528\u4e8e\u4e34\u5e8a\u611f\u67d3\u75c5\u8bca\u65ad\u4e0a\u9274\u5b9a\u75c5\u539f\u4f53\uff0c\u66f4\u597d\u5730\u89e3\u51b3\u4e86\u4ee5\u4e0a\u95ee\u9898\uff0c\u53ea\u9700\u8981\u8f83\u5c11\u83cc\u4f53\uff0c\u53ef\u5bf9\u75c5\u4eba\u76f4\u63a5\u8fdb\u884c\u6837\u54c1\u91c7\u96c6\uff0c\u901a\u8fc7\u5b8f\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u9274\u522b\u51fa\u6240\u6709\u75c5\u539f\u4f53\uff0c\u4e0d\u4f9d\u8d56\u4e8e\u5fae\u751f\u7269\u7684\u5206\u79bb\u548c\u57f9\u517b\uff0c\u53ea\u9700\u8981\u8f83\u77ed\u7684\u65f6\u95f4\uff0c\u4e14\u6570\u636e\u53ef\u9760\u5ea6\u9ad8\u3002<\/p>\n

 <\/p>\n

\u4e09\u3001\u836f\u7269\u654f\u611f\u6027\u5206\u6790<\/span><\/p>\n

 <\/p>\n

1.\u00a0\u836f\u654f\u6027\u5b9e\u9a8c<\/strong><\/p>\n

\u867d\u7136\u7f8e\u56fd\u4e34\u5e8a\u4e0e\u5b9e\u9a8c\u5ba4\u6807\u51c6\u5316\u7814\u7a76\u6240\uff08CLSI\uff09\u5bf9\u4e8e\u4e00\u4e9bNTM\u83cc\u79cd\u6709\u63a8\u8350\u7684\u836f\u654f\u8bd5\u9a8c\u65b9\u6cd5\u548c\u836f\u7269\u4e34\u754c\u6d53\u5ea6\uff0c\u4f46\u8fd9\u4e9b\u65b9\u6cd5\u4ecd\u6709\u5f85\u4e34\u5e8a\u5145\u5206\u5730\u8bc4\u4ef7\u548c\u8c03\u6574\u3002\u5f00\u5c55\u6ca1\u6709\u63a8\u8350\u65b9\u6cd5\u7684\u83cc\u79cd\u7684\u836f\u654f\u8bd5\u9a8c\u65f6\uff0c\u5e38\u89c4\u505a\u6cd5\u662f\u6162\u751f\u957f\u5206\u679d\u6746\u83cc\u591a\u53c2\u7167MTB\u9009\u53d6\u4e34\u754c\u836f\u7269\u6d53\u5ea6\uff0c\u800c\u5feb\u751f\u957f\u5206\u679d\u6746\u83cc\u591a\u53c2\u7167\u666e\u901a\u7ec6\u83cc\u9009\u53d6\u4e34\u754c\u836f\u7269\u6d53\u5ea6\u3002\u4f46\u4e0d\u540c\u79cd\u7684\u5206\u679d\u6746\u83cc\u7684\u8010\u836f\u4e34\u754c\u6d53\u5ea6\u53ef\u80fd\u5b58\u5728\u660e\u663e\u5dee\u5f02\uff0c\u56e0\u6b64\u9700\u8981\u5f00\u5c55\u66f4\u591a\u7684\u4e34\u5e8a\u548c\u57fa\u7840\u7814\u7a76\uff0c\u4ee5\u5efa\u7acb\u9488\u5bf9\u4e0d\u540c\u83cc\u79cd\u7684\u836f\u654f\u8bd5\u9a8c\u65b9\u6cd5\u3002\u4ece\u76ee\u524d\u5df2\u83b7\u5f97\u7684\u6570\u636e\u6765\u770b\uff0cNTM\u611f\u67d3\u7684\u6cbb\u7597\u6548\u679c\u4e3b\u8981\u53d6\u51b3\u4e8e\u83cc\u79cd\uff0c\u5982\u582a\u8428\u65af\u5206\u679d\u6746\u83cc\u3001\u6d77\u5206\u679d\u6746\u83cc\u3001\u82cf\u5c14\u52a0\u5206\u679d\u6746\u83cc\u3001\u87fe\u870d\u5206\u679d\u6746\u83cc\u548c\u6e83\u75a1\u5206\u679d\u6746\u83cc\u7684\u7597\u6548\u8f83\u597d\uff0c\u800cMAC\u3001\u8113\u80bf\u3001\u9f9f\u5206\u679d\u6746\u83cc\u7684\u6cbb\u7597\u7597\u6548\u8f83\u5dee\uff0c\u8868\u660e\u79cd\u5c5e\u5bf9\u836f\u7269\u7684\u654f\u611f\u6027\u81f3\u5173\u91cd\u8981\u3002\u53ea\u6709\u540c\u4e00\u83cc\u79cd\u4e0d\u540c\u83cc\u682a\u5bf9\u836f\u7269\u7684\u654f\u611f\u6027\u5b58\u5728\u5206\u5316\u65f6\uff0c\u624d\u6709\u5fc5\u8981\u5f00\u5c55\u836f\u654f\u8bd5\u9a8c\u3002<\/p>\n

2.\u00a0\u8010\u836f\u6027\u5206\u5b50\u8bca\u65ad<\/strong><\/p>\n

NTM\u548cMTC\u6709\u76f8\u540c\u6216\u7c7b\u4f3c\u7684\u836f\u7269\u9776\u4f4d\uff0c\u4f46NTM\u5bf9\u5f88\u591a\u6297\u7ed3\u6838\u836f\u7269\u5929\u7136\u8010\u836f\uff0c\u8868\u660eNTM\u7ec6\u80de\u58c1\u901a\u900f\u6027\u3001\u836f\u7269\u5916\u6392\u6cf5\u3001\u836f\u7269\u4e0e\u9776\u4f4d\u7684\u4f4e\u4eb2\u548c\u529b\u7b49\u5176\u4ed6\u56e0\u7d20\u8f83\u57fa\u56e0\u591a\u6001\u6027\u5728NTM\u8010\u836f\u4e2d\u53d1\u6325\u7740\u66f4\u4e3a\u91cd\u8981\u7684\u4f5c\u7528\u3002\u4e34\u5e8a\u4e0a\u5bf9\u4e8e\u7ed3\u6838\u5206\u679d\u6746\u83cc\u7684\u5206\u5b50\u68c0\u6d4b\u662f\u6bd4\u8f83\u660e\u786e\u7684\uff0c\u4f46\u975e\u7ed3\u6838\u5206\u679d\u6746\u83cc\u73b0\u5728\u53ea\u6709\u4e2a\u522b\u7684\u4e00\u4e9b\u83cc\u682a\u6211\u4eec\u80fd\u68c0\u6d4b\u5230\uff0c\u5982MAC\u8010\u5927\u73af\u5185\u916f\u7c7b\u836f\u7269\u4e0e23S\u6838\u7cd6\u4f53RNA\u57fa\u56e0\uff08rrl\uff09\u7684\u57fa\u56e0\u7a81\u53d8\u9ad8\u5ea6\u76f8\u5173\uff1b16S\u6838\u7cd6\u4f53RNA\u57fa\u56e0\uff08ITS\uff09\u7a81\u53d8\u4e0e\u8113\u80bf\u5206\u679d\u6746\u83cc\u3001\u9f9f\u5206\u679d\u6746\u83cc\u5bf9\u963f\u7c73\u5361\u661f\u8010\u836f\u76f8\u5173\uff1brpoB\u57fa\u56e0\u7a81\u53d8\u4e0e\u582a\u8428\u65af\u5bf9\u5229\u798f\u5e73\u8010\u836f\u76f8\u5173\u3002\u6709\u9650\u7684\u7814\u7a76\u7ed3\u679c\u63d0\u793a\uff0c\u4e00\u4e9b\u5df2\u77e5\u57fa\u56e0\u7684\u5355\u6838\u82f7\u9178\u591a\u6001\u6027\u53ef\u80fd\u4e0e\u8010\u836f\u6709\u5173\uff0c\u4f46\u73b0\u6709\u7684\u6570\u636e\u4ec5\u62a5\u9053\u4e86\u4e2a\u522b\u836f\u7269\u4e2d\u8f83\u4f4e\u6bd4\u4f8b\u7684\u8010\u836f\u83cc\u682a\u53ef\u80fd\u4e0e\u67d0\u4e00\u57fa\u56e0\u7684\u5e8f\u5217\u591a\u6001\u6027\u6709\u5173\uff0c\u56e0\u6b64\uff0c\u672a\u6765\u8010\u836f\u5206\u5b50\u673a\u5236\u65b9\u9762\u6709\u5f85\u66f4\u6df1\u5165\u7684\u7814\u7a76\uff0c\u624d\u6709\u52a9\u4e8e\u672a\u6765\u5e94\u7528\u5206\u5b50\u624b\u6bb5\u5c3d\u5feb\u53d1\u73b0\u8010\u836f\u83cc\u682a\u3002<\/p>\n

 <\/p>\n

\u56db\u3001\u5b8f\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u5e94\u7528\u4e8eNTM\u68c0\u6d4b\u53ca\u836f\u654f\u6027\u5206\u6790<\/span><\/p>\n

 <\/p>\n

\u968f\u7740\u4e8c\u4ee3\u6d4b\u5e8f\uff08NGS\uff09\u3001\u4e09\u4ee3\u6d4b\u5e8f\u6280\u672f\u7684\u5e7f\u6cdb\u5e94\u7528\uff0c\u5b8f\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u53d1\u751f\u4e86\u5de8\u5927\u53d8\u5316\uff0c\u5728\u83b7\u5f97\u6d77\u91cf\u6570\u636e\u540e\uff0c\u80fd\u591f\u5feb\u901f\u3001\u5168\u9762\u7684\u5206\u6790\u75c5\u539f\u4f53\u7fa4\u843d\u7ed3\u6784\u3002<\/p>\n

\u5b8f\u57fa\u56e0\u7ec4\u5b66\u662f\u4ee5\u67d0\u4e00\u7279\u5b9a\u73af\u5883\u6837\u54c1\u4e2d\u7684\u75c5\u539f\u4f53\u57fa\u56e0\u7ec4\u4e3a\u7814\u7a76\u5bf9\u8c61\uff0c\u4ee5\u6d4b\u5e8f\u5206\u6790\u7684\u624b\u6bb5\uff0c\u4ee5\u75c5\u539f\u4f53\u591a\u6837\u6027\u3001\u79cd\u7fa4\u7ed3\u6784\u3001\u8fdb\u5316\u5173\u7cfb\u3001\u529f\u80fd\u6d3b\u6027\u3001\u76f8\u4e92\u534f\u4f5c\u5173\u7cfb\u53ca\u4e0e\u73af\u5883\u4e4b\u95f4\u7684\u5173\u7cfb\u4e3a\u7814\u7a76\u76ee\u7684\u7684\u75c5\u539f\u4f53\u7814\u7a76\u65b9\u6cd5\u3002\u5b8f\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u76f4\u63a5\u4ece\u6837\u54c1\u4e2d\u63d0\u53d6\u57fa\u56e0\u7ec4DNA\u540e\u6d4b\u5e8f\u5206\u6790\uff0c\u5c06\u6240\u6d4b\u5e8f\u5217\u4e0e\u4e13\u4e1a\u6570\u636e\u5e93\u5bf9\u6bd4\uff0c\u5f97\u51fa\u6837\u672c\u4e2d\u6240\u542b\u7269\u79cd\u4fe1\u606f\uff1a\u901a\u8fc7\u4e25\u683c\u7684\u5b8f\u57fa\u56e0\u7ec4\u62fc\u63a5\uff0c\u83b7\u5f97\u8f83\u957f\u7684DNA\u7247\u6bb5\uff1b\u82e5\u6d4b\u5e8f\u8fbe\u5230\u4e00\u5b9a\u7684\u901a\u91cf\u53ef\u83b7\u5f97\u4e00\u4e2a\u6216\u591a\u4e2a\u75c5\u539f\u4f53\u57fa\u56e0\u7ec4\u8349\u56fe\uff1b\u5728\u6b64\u57fa\u7840\u4e0a\u8fdb\u884c\u529f\u80fd\u5206\u6790\u53ca\u75c5\u539f\u4f53\u7fa4\u843d\u7ed3\u6784\u548c\u591a\u6837\u6027\u5206\u6790\u3002<\/p>\n

\u76ee\u524d\u8be5\u6280\u672f\u5df2\u5e7f\u6cdb\u5e94\u7528\u4e8e\u5de5\u4e1a\u751f\u4ea7\u3001\u98df\u54c1\u5b89\u5168\u3001\u533b\u5b66\u7814\u7a76\u53ca\u4e34\u5e8a\u8bca\u65ad\u7b49\u9886\u57df\uff0c\u5728\u4e34\u5e8a\u4e0a\u7684\u5e94\u7528\u5982\u611f\u67d3\u7c7b\u578b\u8bca\u65ad\u3001\u8010\u836f\u548c\u654f\u611f\u5206\u6790\u3001\u4f20\u67d3\u75c5\u7684\u9632\u63a7\u7b49\u3002\u8be5\u65b9\u6cd5\u7684\u5e94\u7528\u5728\u4e34\u5e8a\u4e0a\u5bf9\u75c5\u539f\u4f53\u68c0\u6d4b\u3001\u9884\u6d4b\u5bf9\u836f\u7269\u654f\u611f\u6027\u65b9\u9762\u5df2\u7ecf\u53d6\u5f97\u4e86\u8fdb\u5c55\u3002<\/p>\n

\u968f\u7740\u79d1\u5b66\u7684\u8fdb\u6b65\u4e0e\u533b\u7597\u7684\u53d1\u5c55\uff0c\u6211\u56fd\u7ed3\u6838\u75c5\u75ab\u60c5\u9010\u6b65\u5f97\u5230\u63a7\u5236\uff0c\u800c\u6211\u56fd\u7684\u975e\u7ed3\u6838\u5206\u679d\u6746\u83cc\u611f\u67d3\u95ee\u9898\u5374\u8d8a\u6765\u8d8a\u7a81\u51fa\uff0c\u4e34\u5e8a\u5bf9NTM\u611f\u67d3\u75be\u75c5\u7684\u8bca\u65ad\u548c\u6cbb\u7597\u95ee\u9898\u6025\u9700\u89e3\u51b3\u3002\u5b8f\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u65b9\u6cd5\u907f\u5f00\u4e86\u4f20\u7edf\u65b9\u6cd5\u75c5\u539f\u4f53\u57f9\u517b\u3001\u5206\u79bb\u7684\u5c40\u9650\u6027\uff0c\u76f4\u63a5\u5206\u6790\u6837\u672c\u4e2d\u75c5\u539f\u4f53\uff0c\u66f4\u597d\u5730\u89e3\u51b3\u76ee\u524d\u7ed3\u6838\u548c\u975e\u7ed3\u6838\u9274\u5b9a\u56f0\u96be\u3001\u8bca\u65ad\u65f6\u95f4\u5468\u671f\u957f\u7b49\u95ee\u9898\u3002\u76ee\u524d\u4e3a\u6b62\uff0c\u57fa\u56e0\u6d4b\u5e8f\u662f\u6700\u7cbe\u51c6\u7684\u9274\u5b9aNTM\u83cc\u79cd\u7684\u65b9\u6cd5\uff0c\u5e76\u4e14\u6d4b\u5e8f\u53ea\u9700\u8981\u6781\u5c11\u7684\u83cc\u3002<\/p>\n

\u5c06\u5b8f\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u6280\u672f\u5e94\u7528\u4e8e\u4e34\u5e8a\u68c0\u6d4bNTM\uff0c\u5bf9\u4e8e\u4e34\u5e8a\u533b\u751f\u5c06\u89e3\u51b3\u4e86\u4e00\u4e2a\u68d8\u624b\u7684\u95ee\u9898\uff0c\u8be5\u65b9\u6cd5\u8f85\u52a9\u4e34\u5e8a\u8bca\u65ad\u4ee5\u53ca\u5bf9\u836f\u7269\u6cbb\u7597\u63d0\u4f9b\u4e86\u53ef\u9760\u4f9d\u636e\uff0c\u901a\u8fc716sRNA\u6d4b\u5e8f\u68c0\u6d4b\u9ad8\u5ea6\u4fdd\u5b88\u768416s\u6838\u7cd6\u4f53\u4e9a\u57fa\uff0c\u51c6\u786e\u9274\u5b9a\u3001\u5206\u6790\u6837\u54c1\u4e2d\u7684\u75c5\u539f\u4f53\u662f\u5426\u542b\u6709NTM\uff0c\u540c\u65f6\u5bf9\u6d4b\u5e8f\u75c5\u539f\u4f53\u8010\u836f\u6027\u8fdb\u884c\u9884\u6d4b\uff0c\u901a\u8fc7\u4e0e\u8010\u836f\u76f8\u5173\u57fa\u56e0\u8fdb\u884c\u6bd4\u5bf9\uff0c\u786e\u5b9a\u8010\u836f\u57fa\u56e0\u662f\u5426\u53d1\u751f\u57fa\u56e0\u7a81\u53d8\u6765\u5b8c\u6210\u75c5\u539f\u4f53\u5bf9\u836f\u7269\u8010\u836f\u6027\u7684\u9884\u6d4b\u3002\u5b8f\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u6280\u672f\u5e94\u7528\u4e8eNTM\u68c0\u6d4b\u53ca\u8010\u836f\u5206\u6790\uff0c\u53ef\u8f83\u5bb9\u6613\u5730\u5728\u77ed\u65f6\u95f4\u5185\u533a\u5206\u7ed3\u6838\u5206\u679d\u6746\u83cc\u548c\u975e\u7ed3\u6838\u5206\u679d\u6746\u83cc\uff0c\u51cf\u5c11\u4e86\u8bef\u8bca\u51e0\u7387\u3001\u8bca\u65ad\u65f6\u95f4\uff0c\u5e76\u4e14\u6839\u636e\u836f\u654f\u6027\u5206\u6790\u66f4\u597d\u5730\u786e\u5b9a\u836f\u7269\uff0c\u907f\u514d\u4e86\u8010\u836f\u6027\u5e26\u6765\u7684\u9519\u8bef\u7528\u836f\u95ee\u9898\u3002<\/p>\n

 <\/p>\n

\u53c2\u8003\u6587\u732e\uff1a<\/span><\/p>\n

    \n
  1. \u4e2d\u534e\u533b\u5b66\u4f1a\u7ed3\u6838\u75c5\u5b66\u5206\u4f1a.\u300a\u975e\u7ed3\u6838\u5206\u679d\u6746\u83cc\u75c5\u5b9e\u9a8c\u5ba4\u8bca\u65ad\u4e13\u5bb6\u5171\u8bc6\u300b.\u4e2d\u534e\u7ed3\u6838\u4e0e\u547c\u5438\u6742\u5fd7;2016,39(6):438-443.<\/span><\/li>\n
  2. Yon Ju Ryu,Won-Jung Koh,M,Charles L.Daley. Diagnosis and Treatment of Nontuberculous Mycobacterial Lung Disease:Clinicians\u2019 Perspective.Tuberc Respir Dis;2016 Apr.79(2):74-84.<\/span><\/li>\n
  3. Kendall BA,Winthrop KL.Update on the epidemiology of pulmonary nontuberculous mycobacterial infections.Semin Respir Crit Care Med 2013;34:87-94.<\/span><\/li>\n
  4. Adjemian J,Prevots DR,Gallagher J,et al.Lack of adherence to evidence-based treatment guidelines for nontuberculous mycobacterial lung disease.Ann Am Thorac Soc 2014;11:9-16.<\/span><\/li>\n<\/ol>\n

     <\/p>\n

    \u6676\u8bfa\u751f\u7269\u6280\u672f\u670d\u52a1<\/span><\/p>\n

     <\/p>\n

    \u3010\u7ed3\u6838\u5206\u679d\u6746\u83cc\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u6280\u672f\u670d\u52a1\u3011<\/p>\n

      \n
    • \u670d\u52a1\u5185\u5bb9
      \n\u7ed3\u6838\u5206\u679d\u6746\u83cc\u57fa\u56e0\u7ec4\u63d0\u53d6\u3001\u8d28\u63a7\u3001\u5efa\u5e93\u3001\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u4ee5\u53ca\u8010\u836f\u548c\u654f\u611f\u5206\u6790\u3002<\/li>\n
    • \u6d4b\u5e8f\u57fa\u672c\u53c2\u6570
      \n\u6d4b\u5e8f\u8bfb\u957f\u53cc\u7aef 150 bp\uff08PE150\uff09, \u8fc7\u6ee4\u540e\u5355\u6837\u672c\u9ad8\u8d28\u91cf\u6570\u636e\u91cf\uff08>Q30\uff09\u5e73\u5747 900 Mb \u4ee5\u4e0a\uff0c\u539f\u59cb\u6570\u636e\u5e73\u5747 1000 Mb \u4ee5\u4e0a\u3002<\/li>\n
    • \u8010\u836f\u5206\u6790
      \n\u4e0e\u56fd\u5185\u6743\u5a01\u5355\u4f4d\u5408\u4f5c\u5efa\u7acb\u4e86\u5f3a\u5927\u7684\u6570\u636e\u5e93\u548c\u4e91\u7aef\u7ed3\u6838\u5206\u679d\u6746\u83cc\u5168\u57fa\u56e0\u7ec4\u5e8f\u5217\u5206\u6790\u5e73\u53f0\uff0c\u53ef\u7ed3\u5408NGS\u7ed3\u679c\u5bf9\u6d4b\u5e8f\u83cc\u682a\u6297\u7ed3\u6838\u836f\u7269\u654f\u611f\u6027\u548c\u8010\u836f\u6027\u8fdb\u884c\u5168\u9762\u9884\u6d4b\u5206\u6790\uff0c\u8f93\u51fa\u5206\u6790\u7ed3\u679c\u3002\u9488\u5bf94\u79cd\u4e00\u7ebf\u836f\u7269\u5f02\u70df\u80bc\u3001\u5229\u798f\u5e73\u3001\u4e59\u80fa\u4e01\u9187\u3001\u5421\u55ea\u9170\u80fa\u63d0\u4f9b\u8010\u836f\u53ca\u654f\u611f\u6027\u9884\u6d4b\uff0c\u5bf910\u79cd\u4e8c\u7ebf\u836f\u7269\uff08\u94fe\u9709\u7d20\uff0c\u4e59\u786b\u5f02\u70df\u80fa\uff0c\u963f\u7c73\u5361\u661f\uff0c\u5377\u66f2\u9709\u7d20\uff0c\u5361\u90a3\u9709\u7d20\u3001\u5bf9\u6c28\u57fa\u6c34\u6768\u9178\u3001\u5229\u5948\u5511\u80fa\u3001\u6c2f\u6cd5\u9f50\u660e\u3001\u6c1f\u55b9\u8bfa\u916e\u3001\u8d1d\u8fbe\u55b9\u5549\uff09\u63d0\u4f9b\u8010\u836f\u9884\u6d4b\uff0c\u5bf9\u4e8e\u591a\u8010\u836f\u7ed3\u6838\u5206\u679d\u6746\u83cc\u4e34\u5e8a\u7528\u836f\u5177\u6709\u6307\u5bfc\u610f\u4e49\u3002<\/li>\n
    • \u83cc\u682a\u9057\u4f20\u8ddd\u79bb\u5206\u6790
      \n\u6bd4\u8f83\u4e0d\u540c\u83cc\u682a\u95f4\u9057\u4f20\u8ddd\u79bb\uff0c\u53ef\u7528\u4e8e\u9274\u5b9a\u7ed3\u6838\u75c5\u8fd1\u671f\u4f20\u64ad\u6216\u66b4\u53d1\u4e8b\u4ef6\uff0c\u4e3a\u6d41\u884c\u75c5\u5b66\u8c03\u67e5\u548c\u7ed3\u6838\u75c5\u9632\u63a7\u63d0\u4f9b\u7406\u8bba\u4f9d\u636e\u3002<\/li>\n<\/ul>\n

      \u3010\u7ed3\u6838\u5206\u679d\u6746\u83cc\u57fa\u56e0\u6572\u9664\u6280\u672f\u670d\u52a1\u3011<\/p>\n

        \n
      • \u91c7\u7528\u566c\u83cc\u4f53\u4ecb\u5bfc\u7684\u540c\u6e90\u91cd\u7ec4\u8fdb\u884c\u57fa\u56e0\u6572\u9664\uff1b<\/li>\n
      • \u9633\u6027\u738795%\u4ee5\u4e0a\uff1b<\/li>\n
      • \u5df2\u6210\u529f\u6784\u5efa\u7ed3\u6838\u5206\u679d\u6746\u83cc4000\u4f59\u4e2a\u57fa\u56e0\u7684\u566c\u83cc\u4f53\u6587\u5e93\u548c\u57fa\u56e0\u8fc7\u8868\u8fbe\u8d28\u7c92\uff1b<\/li>\n
      • \u5e7f\u6cdb\u9002\u7528\u4e8e\u7ed3\u6838\u5206\u679d\u6746\u83cc\u3001\u803b\u57a2\u5206\u679d\u6746\u83cc\u3001\u725b\u7ed3\u6838\u5206\u679d\u6746\u83cc\u3001\u6d77\u5206\u679d\u6746\u83cc\u3002<\/li>\n
      • \u53e6\u6709pJV53\u4ecb\u5bfc\u7684\u57fa\u56e0\u6572\u9664\u3002<\/li>\n<\/ul>\n

        \u3010\u7ed3\u6838\u5206\u679d\u6746\u83cc\u91cd\u8981\u514d\u75ab\u539f\u86cb\u767d\u4ea7\u54c1\u3011<\/p>\n

          \n
        • \u7eaf\u5ea6\u9ad8\uff1a\u5927\u4e8e95%\uff1b<\/li>\n
        • \u5185\u6bd2\u7d20\u4f4e\uff1a\u5c0f\u4e8e0.1EU\/\u03bcg\uff1b<\/li>\n
        • \u5916\u6e90\u56e0\u5b50\u542b\u91cf\u4f4e\uff1b<\/li>\n
        • \u6210\u719f\u7684\u86cb\u767d\u8d28\u7eaf\u5316\u5e73\u53f0\uff1b<\/li>\n
        • \u53ef\u4e2a\u6027\u5316\u5b9a\u5236\uff1b<\/li>\n
        • \u5927\u5305\u88c5\u53ef\u514d\u8d39\u5206\u88c5\u3002<\/li>\n<\/ul>\n

           <\/p>\n

          \u8054\u7cfb\u6211\u4eec<\/span><\/p>\n

           <\/p>\n

          \u4e0a\u6d77\u6676\u8bfa\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8<\/p>\n

          \u7535\u8bdd\uff1a0757-29328131-616<\/p>\n

          \u624b\u673a\/\u5fae\u4fe1\uff1a13392273325<\/p>\n

          Q Q\uff1a2775427010<\/p>\n

          \u4e1a\u52a1\uff1ainfo@gene-optimal.com<\/p>\n

          \u62db\u8058\uff1ahr@gene-optimal.com<\/p>\n

          \u5730\u5740\uff1a\u5e7f\u4e1c\u7701\u4f5b\u5c71\u5e02\u4f5b\u5c71\u65b0\u57ce\u5cad\u5357\u5927\u90532\u53f7\u4e2d\u6b27\u4e2d\u5fc3A\u680b\uff08\u5206\u516c\u53f8\uff09<\/p>\n

           <\/p>\n

          \u7248\u6743\u58f0\u660e\uff1a\u672c\u6587\u7cfb\u6676\u8bfa\u751f\u7269\u7f16\u8bd1\u6574\u7406\uff0c\u672a\u7ecf\u6676\u8bfa\u751f\u7269\u6388\u6743\uff0c\u4e0d\u5f97\u8f6c\u8f7d\u548c\u4f7f\u7528\uff0c\u5982\u9700\u83b7\u53d6\u6388\u6743\uff0c\u8bf7\u8054\u7cfb\u6211\u4eec\u3002<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

          \u6211\u56fd\u5386\u6b21\u7ed3\u6838\u75c5\u6d41\u884c\u75c5\u5b66\u8c03\u67e5\u8d44\u6599\u663e\u793a\uff0c\u975e\u7ed3\u6838\u5206\u679d\u6746\u83cc…<\/p>\n","protected":false},"author":1,"featured_media":41521,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"_links":{"self":[{"href":"https:\/\/www.gene-optimal.com\/wp-json\/wp\/v2\/posts\/41515"}],"collection":[{"href":"https:\/\/www.gene-optimal.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.gene-optimal.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.gene-optimal.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.gene-optimal.com\/wp-json\/wp\/v2\/comments?post=41515"}],"version-history":[{"count":0,"href":"https:\/\/www.gene-optimal.com\/wp-json\/wp\/v2\/posts\/41515\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.gene-optimal.com\/wp-json\/wp\/v2\/media\/41521"}],"wp:attachment":[{"href":"https:\/\/www.gene-optimal.com\/wp-json\/wp\/v2\/media?parent=41515"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.gene-optimal.com\/wp-json\/wp\/v2\/categories?post=41515"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.gene-optimal.com\/wp-json\/wp\/v2\/tags?post=41515"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}